In-vitro cytotoxicity activity of potato (Solanum tuberosum. L) peel extracts against human gingival fibroblasts

Potato peel is often regarded as waste although it contains phenolic compounds, glycoalkaloids, and flavonoid. This study aimed to evaluate the effect of different concentrations potato extracts on viability Human Gingival Fibroblasts (HGF). were prepared by a maceration technique. The 96-well tissue culture micro titre plates seeded with HGF at density 2×104 cells/100 μL incubated for 24 hours. Next, 100 concentration 62.5 μg/mL, 125 250 500 1000 μg/mL medium (control) dispensed into well cell culture. Each was evaluated its 3 replicate samples. results MTT test analyzed statistically using one-way ANOVA LSD test. mean standard deviation viable after extract 98.67% ± 3.56, 88.34% 0.79, 55.42% 3.96, 28.33% 0.60, 26.26% 0.53, respectively. percentage non-viable increased an increase in extract. result showed significant influence various (p<0.05). LSD-test difference among all treatment groups A higher line considered non-cytotoxic.